Home > News > EQUIA® Restorative system: outstanding performance confirmed by several long-term clinical trials
EQUIA® Restorative system: outstanding performance confirmed by several long-term clinical trials

Date Released: Oct 20, 2020

EQUIA Research overview


EQUIA® Restorative system: outstanding performance confirmed by several long-term clinical trials1-16 


Introduced in 2007, the EQUIA restorative system quickly shown to be a new standard in restorative technology, offering aesthetically pleasing bulk-fill posterior restorations and an advanced option to overcome limitations of amalgam, composite and conventional glass ionomer fillings.1-12 Over the years, EQUIA has inspired a number of prominent research groups to evaluate its clinical performance in several short- and long-term trials.1-16


Mounting evidence for EQUIA

A significant number of articles published in high-ranked journals brought in light the remarkable performance of EQUIA in Class I and II restorations after 2- and 3-year follow-up periods (Friedl et al1; Klinke et al2; Olegario et al3; Fatidou et al4; Lopez et al5). Two additional studies (Turkun et al6 and Basso et al7) evaluated EQUIA restorations after longer periods of 6 and 7 years respectively, concluding about its reliability and durability for Class I, II and V restorations.

Other leading studies compared EQUIA to conventional resin composites. For instance, Menezes Silva et al8 and Kupietzky et al9 demonstrated similar success rates of EQUIA and composite resin in Class II restorations after 3 years.

 After a 5-year trial, Molina et al10 revealed the optimal performance of EQUIA to treat special care patients. EQUIA also shown to be a trustworthy restorative option for non-carious cervical lesions after 1 and 3-years as described by Vaid et al11 and Celik et al12 respectively. A randomized controlled trial leaded by Heck et al 13 showed, after a 6-year follow-up, the acceptable performance of EQUIA to restore two- or three-surface class II restorations.

 Finally, Gurgan et al14. conducted a notable 10-year clinical trial reporting an outstanding success rate of 100% for the EQUIA restorative system in class I and II cavities.


Glass Hybrid materials: a new era of performance

Building on the extensive and positive clinical evidence of the EQUIA restorative system, GC introduced in 2015 EQUIA Forte, the first glass hybrid, and offer an unprecedented option for long-term restorations.

 The interim results of clinical studies show the suitability of EQUIA Forte as a long-term material to restore extended size Class II cavities[1]. Gurgan S. et al15 compared EQUIA Forte to a micro-hybrid composite concluding that, after 4 years, both materials presented optimal surface and marginal adaptation characteristics. The EQUIA Forte multicenter study (Miletic I. et al16) compares the glass-hybrid to a nano-hybrid resin composite (Tetric EvoCeram, Ivoclar Vivadent) and the two-year interim results have shown similar clinical performance for both materials.

Backed by years of extensive research and academically reviewed publications, this literature review provides clinicians with the unwavering confidence in glass hybrid restorative systems as an optimal long-term restorative alternative.

The latest Glass hybrid, EQUIA Forte HT, offers increased aesthetics and strength compared to its predecessor EQUIA Forte, confirming that the glass-hybrid are a trustworthy long-term restorative option to the dentist while still being cost effective for patients.



This study was led by Dr Katrin Friedl, private dentist in Regensburg, Germany. The study is registered in ClinicalTrials.gov (No.: NCT02717520). This research was supported by This research was supported by GC Europe and GC Germany. Study available from: Friedl K et al, Clinical performance of a new glass ionomer-based restoration system: a retrospective cohort study Dent Mater. 2011 Oct;27(10):1031-7.doi:10.1016/j.dental.2011.07.004 https://pubmed.ncbi.nlm.nih.gov/21840585/


This study was led by Prof. Thomas Klinke, University of Greifswald, Department of Prosthodontics, Geriatric Dentistry and Medical Materials Science, Greifswald , Germany. The study was registered at Deutsches Register Klinischer Studien (German register of clinical trials) on 6 September 2012 under DRKS-ID: DRKS00004220. This research was funded by was funded by GC Japan, GC Europe, and GC Germany. Study available from: Klinke T et al. Clinical performance during 48 months of two current glass ionomer restorative systems with coatings: a randomized clinical trial in the field Trials. 2016 May 8;17(1):239. doi: 10.1186/s13063-016-1339-8 https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-016-1339-8


This study was led by Dr Daniela Prócida Raggio, University of Sao Paulo, Brazil. This was a three-arm parallel randomized clinical trial registered in the website www.clinicaltrials.gov (#NCT02217098). This study was supported by FAPESP-Fundação de Amparo à Pesquisa do Estado de São Paulo (grant numbers: 2015/00565-3 and 2013/11236-5). This study was partially supported by National Council for Scientific and Technological Development from the Brazilian Government (grant numbers: 309521/2015-7 and 306304/2015-5). Study available from: Olegário C et al, Glass carbomer and compomer for ART restorations: 3-year results of a randomized clinical trial Clin Oral Investig. 2019 Apr;23(4):1761-1770.  doi: 10.1007/s00784-018-2593-9 https://pubmed.ncbi.nlm.nih.gov/30171345/


This study was led by Dr Christina Fotiadou Ludwig-Maximilians-University of Munich, Germany. Study available from: Fatiadou et al, A 3-year controlled randomized clinical study on the performance of two glass ionomer cements in Class II cavities of permanent teeth Quintessence Int.2019;50(8):592-602.doi:10.3290/j.qi.a42692 https://pubmed.ncbi.nlm.nih.gov/31286115/


This study was led by Dr Lily Zelada Lopez, San Martin de Porres University, Chiclayo, Peru. The study was financially supported by the GC Corporation (Tokyo, Japan) providing the restorative materials, instruments and equipments and by the Dental School San Martin de Porres University (Lima, Peru). Study available from: Lopez L et al, Randomized clinical trial evaluating proximal retentions on ART restorations J Dent Res Vol 98 (Spec Iss A):2120 https://iadr2019.zerista.com/event/member/584705


This study was led by Prof. Lezize Sebnem Turkun, Dept. of Restorative Dentistry Bornova, Ege University School of Dentistry, Izmir, Turkey. GC Europe and SDI Australia provided the materials free of charge for this clinical trial. Study available from: Türkün S et al, A prospective six-year clinical study evaluating reinforced glass ionomer cements with resin coating on posterior teeth: quo vadis? Oper Dent. 2016 Nov/Dec;41(6):587-598.  doi.org/10.2341/15-331-C https://pubmed.ncbi.nlm.nih.gov/27571238/


This study was led by Prof. Matteo Basso, University of Milan | UNIMI · Galeazzi Orthopaedic Institute IRCCS. Study available from: Basso M et al, 7 Years, multicenter, clinical evaluation on 154 permanent restorations made with a glass ionomer-based restorative system. J Dent Res Vol 95 (Spec Iss B): 0446. 2016.doi:10.13140/RG.2.1.1603.2249 https://iadr.abstractarchives.com/abstract/16iags-2474719/7-years-multicentre-clinical-evaluation-on-154-permanent-restorations-made-with-a-glassionomer-based-restorative-system


This study was led by Dr Rafael Menezes-Silva, University of São Paulo , Bauru-SP , Brazil. This study was supported by GC Corp. Study available from: Menezes-silva I et al, Three-year randomized clinical trial evaluating ART and composite resin restorations J Dent Res Vol 98 (Spec Iss A):3732 https://iadr2019.zerista.com/event/member/582959


This study was led by A. Kupietzky, Department of Pediatric Dentistry, Hebrew University - Hadassah School of Dental Medicine, Jerusalem, Israel. Study available from: Kupietzky A et al, Long-term clinical performance of heat-cured high-viscosity glass ionomer class II restorations versus resin-based composites in primary molars: a randomized comparison trial.  Eur Arch Pediatric Dent. 2019 Feb 28. doi: 10.1007/s40368-019-00423-x https://pubmed.ncbi.nlm.nih.gov/30820833/


This study was led by Prof. Gustavo Molina, Universidad Nacional de Córdoba. Study available from: Molina G et al, Five-year follow-up of ART and CRT in patients with disability. J Dent Res Vol 98 (Spec Iss A): 1357, https://iadr2019.zerista.com/event/member/583146


This study was led by Dr Deepa Sunil Vaid, Dept of Conservative Dentistry and Endodontics, K.M. Shah Dental College, Sumandeep Vidyapeeth University, Vadodara, Gujarat, India. Study available from: Vaid DS et al, One-year comparative clinical evaluation of EQUIA with resin-modified glass ionomer and a nanohybrid composite in non-carious cervical lesions. Conserv Dent. 2015 Nov-Dec;18(6):449-52.doi:10.4103/0972-0707.168805 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693316/


This study was led by Esra Uzer Celik, Department of Restorative Dentistry, Faculty of Dentistry, İzmir Katip Çelebi University, Izmir, Turkey. Funding for this study was provided by the Scientific Research Projects Coordinatorship of Izmir Katip Celebi University. Study available from: Celik U et al, Three-year clinical evaluation of high-viscosity glass ionomer restorations in  non-carious cervical lesions: a randomized controlled split-mouth clinical trial Clin Oral Investig. 2019 Mar;23(3):1473-1480.doi:10.1007/s00784-018-2575-y https://pubmed.ncbi.nlm.nih.gov/30120605/


This study was led by Dr Katrin Heck, Department of Conservative Dentistry and Periodontology, University Hospital, Ludwig-Maximilians-University Munich, Germany. The study was mainly financed by the GC Corporation. Study available from: Heck K et al, Six-year results of a randomized controlled clinical trial of two glass ionomer cements in class II cavities J Dent. 2020 un;97:103333.doi:10.1016/j.jdent.2020.103333 https://pubmed.ncbi.nlm.nih.gov/32305380/


This study was led by Prof. Sevil Gurgan, Hacettepe University, Faculty of Dentistry, Department of Restorative Dentistry, Sıhhiye, Ankara Turkey. Study available from: Gurgan S et al, A randomized controlled 10 years follow-up of a glass ionomer restorative material in class I and class II cavities  J Dent. 2020 Mar;94:103175.doi:10.1016/j.jdent.2019.07.013 https://pubmed.ncbi.nlm.nih.gov/31351909/


This study was led by Prof. Sevil Gurgan, Hacettepe University, Faculty of Dentistry, Department of Restorative Dentistry, Sıhhiye, Ankara Turkey.

Study available from: Gurgan S. et al, 48-Month clinical performance of a glass hybrid in extended size class II cavities. J Dent Res Vol 99 (Spec Iss A): 1389 https://iadr.abstractarchives.com/abstract/20iags-3327309/48-month-clinical-performance-of-a-glass-hybrid-in-extended-size-class-ii-cavities


The study was led by Dr. Ivana Miletić, Professor in the Department of Endodontics and Restorative Dentistry, at Zagreb University, Croatia, working with a team of highly regarded professors from four European dental schools, as cited above. The study is registered in ClinicalTrials.gov (No.: NCT02717520). This research was supported by research grants from the University of Zagreb, Croatia. GC Europe provided materials free of charge. Study available from: Miletić I, Baraba A, Basso M, et al. Clinical Performance of a Glass-Hybrid System Compared with a Resin Composite in the Posterior Region: Results of a 2-year Multicenter Study. J Adhes Dent. 2020;22(3):235-247. doi:10.3290/j.jad.a44547. https://jad.quintessenz.de/index.php?doc=abstract&abstractID=44547/ 









Caption: Either GC EQUIA product line OR GC EQUIA and EQUIA Forte HT OR GC EQUIA Forte  

EQUIA Forte is for use only by a dental professional in the recommended indications. Always read and follow the instructions for use. EQUIA Forte is contraindicated for pulp capping. Avoid use of this product in patients with known allergies to glass ionomer cement, acrylate monomer, methacrylate monomer or methacrylate polymer. In case of contact with oral tissue or skin, immediately remove with a sponge or cotton pellet. After the restorative treatment is finished, rinse thoroughly with water. In case of contact with eyes, flush immediately with water and seek medical attention. In rare cases the product may cause sensitivity in some people. If any such reactions are experienced, discontinue the use of the product and refer to a physician. For more information visit www.gcaustralasia.com or contact your GC Specialist.



[1] See IFU or technique guide for class II cavity preparations 

GC Australia
PO Box 504, Matraville
Sydney NSW 2036
Tel: +61-2-9301 8200

Follow Us
Stay Connected
Company News